منابع مشابه
Dopamine receptors in a songbird brain
Dopamine is a key neuromodulatory transmitter in the brain. It acts through dopamine receptors to affect changes in neural activity, gene expression, and behavior. In songbirds, dopamine is released into the striatal song nucleus Area X, and the levels depend on social contexts of undirected and directed singing. This differential release is associated with differential expression of activity-d...
متن کاملPhysiological and Pharmacopathological Role of Dopamine Receptors and Brain Dopamine Systems
This article has no abstract
متن کاملMultiple receptors for brain dopamine.
This study was done to obtain direct in vitro evidence for the possible existence of more than one type of dopaminergic binding site in homogenates of the caudate nucleus from calf brain. Five radioligands for dopaminergic sites were tested. The inhibitions of two agonist radioligands ([3H]dopamine, [3H]apomorphine) by haloperidol, chlorpromazine, or piflutixol were biphasic. The inhibitions of...
متن کاملDopamine Receptors in the Human Brain
In 1952, Delay and Deniker reported the use of chlorpromazine (Thorazine) to treat psychosis. They initiated an important advance in the treatment of schizophrenia without a clear understanding of the mechanisms underlying the drug's therapeutic effect. In 1963, Carlsson first postulated that the effects of neuroleptics were secondary to dopamine receptor blockade. Also at this time researchers...
متن کاملLocalization of androgen receptors and estrogen receptors in the same cells of the songbird brain.
Estrogens and androgens each have unique effects but act together for the neural differentiation and control of sexual behaviors in male vertebrates, such as the canary. The neuronal basis for these synergistic effects is elusive because the spatial relation between estrogen target cells and androgen target cells is unknown. This study localized estrogen receptor (ER)-containing cells by using ...
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ژورنال
عنوان ژورنال: The Journal of Comparative Neurology
سال: 2010
ISSN: 0021-9967,1096-9861
DOI: 10.1002/cne.22255